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KMID : 0383019920230010001
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Alumni Bulletin of Internal Medicine
1992 Volume.23 No. 1 p.1 ~ p.18
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Studies on Differential Diagnosis between Liver Cirrhosis
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Abstract
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the total sarum protein content was measured and the serum protein fractionation swas made by paper electrophoresis, and the Levels of the serum α, β-lipoprotein cholesterols, β-lipoprotein, serum vitamin B12 and serum transaminase (S-GOT,
S-GPT)
activities were determined in varying liver disease, i.e., liver cirhosis, hepatoma, hepatitis, cholelithiasis and liver abscess.
@ES The results observed are summarized as follows.
@EN 1) The total serum protein contents showed a slight decrease in the liver cirrhosis land heptoma comparing to the normal value.
2) The paper electropherograms of serum protein revealed a general decrease in serum albumin in the liver cirhosis and in other liver diseases as well. The serum globulins, on the other hand, increased and particularly γ-globulin showed the
highest
increase in liver cirrhosis. Also in the other liver diseases investigated the γ-globulin showed the great increase and β-globulin. α2, α1-globulin were also increased in their order of magnitude.
3) The levles of the serum α, β-lipoprotein cholesterols were found to increase in liver cirrhosis comparing to the normal value, and similar increase was also observed in hepatoma, hepatitis, and cholelithiasis. The α/β+β and β/α+β
lipoprotein
cholesterol ratios did not differn significantly in the liver diseases studies studied, but the β/α ratio showed a tendency of decrease comparing to the normal value.
4) the serum β-lipoprotein showed a general increase in all the liver diseases under investigation, and the most significant increase was found in cholelithiasis.
5) The levels of serum vitamin B12 were significantly increased in liver cirrhosis, hepatoma, liver abscess and cholelithiasis in this order of magnitude.
6) The serum transaminase activities of liver cirrhosis, hepatoma and cholelithiasis showed a general increase and the most significant increase in S-GOT and S-GPT was observed in liver cirrhosis.
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KEYWORD
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